Effect of miR-21 and miR-30b/c on TRAIL-induced apoptosis in glioma cells
نویسندگان
چکیده
منابع مشابه
Effect of Estradiol on miR-21; miR-155 Expression in promyelocytic leukemia-derived cell line NB4
Background: Due to the estrogen participation in modulating the proliferation and commitment of stem cells and the effects of miR-21 and miR-155 expression on reduced proliferation and colony formation of acute myeloid leukemia (AML), the aim of the present study was to evaluate the effect of estradiol on expression of miR-21 and miR-155 in the NB4 cell line, as an acute promyelocytic leukemia ...
متن کاملThe effect of miR-21 on SWOZ2 glioma cells and its biological mechanism.
PURPOSE To investigate the role of micro RNA-21 (miR- 21) in human glioma cells and its potential disease-causing mechanism. METHODS jetPRIME was used to transfect the miR-21- mimics and its negative control into SWOZ2 human glioma cells. Real-time fluorescence quantitative PCR assay was used to measure differences in the expression of miR-21 in SWOZ2 glioma cells, SWOZ2-miR-21-mimics cells, ...
متن کاملDeregulation of miR-21 and miR-155 and their putative targets after silibinin treatment in T47D breast cancer cells
Objective(s):MicroRNAs (miRNAs) are a class of short RNAs that control the biological processes including cell proliferation, apoptosis and development. Aberrant expression of miRNAs was determined in the different stages of tumor development and metastasis. To study the effect of silibinin on miRNAs expression, we evaluated quantitative expression of miR-21 and miR-155 as two oncomiRs and seve...
متن کاملUp-regulation of miR-21 decreases chemotherapeutic effect of dendrosomal curcumin in breast cancer cells
Objective(s): Despite the good results of anticancer activities by curcumin, there are some hurdles that limit the use of curcumin as an anticancer agent. Many methods were examined to overcome this defect like the use of the dendrosomal curcumin (DNC). There is increasing evidence that miRNAs play important roles in biological processes. In this study, we focus on the roles of microRNA-21 in t...
متن کاملMiR-21 enhanced glioma cells resistance to BCNU
worldwide. Nowadays, strategies to treat these tumors include surgery, radiation therapy and chemotherapy. Despite advances in these strategies, the prognosis for glioma has not significantly improved recently1, and the ineffectiveness of current treatments can be ascribed to chemo-resistance partially. Recent studies have shown that glioma is resistant to the cytotoxic effects of chemotherapeu...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Oncogene
سال: 2012
ISSN: 0950-9232,1476-5594
DOI: 10.1038/onc.2012.410